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Neobe Therapeutics

Careers - archived posting

Senior Scientist - Synthetic Biology

Engineering bacteria and building a cloning platform for screening selected biosensors, and leading the in vitro and ex vivo work that tests the candidates it produces.

Employment
Full time, permanent
Location
Neobe's laboratory, Stevenage Bioscience Catalyst, Hertfordshire
Applications
Monday 15 April 2024 to Friday 26 April 2024

Closed

This posting is closed. It was open from Monday 15 April 2024 to Friday 26 April 2024.

It is kept here as a record of the work and the terms offered. Speculative applications are always welcome at info@neobetherapeutics.com.

01

About us

Following a significant milestone in our ambitious and exciting growth plans, achieving a successful seed round of over $2m, we are ready to grow our team to advance our pioneering work in immuno-oncology.

Neobe Therapeutics is an innovation-driven Biopharmaceutical start-up developing the next generation of therapeutics in Oncology. At Neobe we are engineering safe strains of tumour colonising bacteria to locally remove stromal barriers to infiltration in immune excluded tumours. Bacteria have been shown to colonise, proliferate and deliver payloads to tumours, making them the ideal candidate for this approach.

02

Your key areas of responsibility

  • Engineering bacteria and performing molecular biology techniques to develop a cloning platform for screening selected biosensors.
  • Lead planning and execution of in vitro and ex vivo complex experimental work to test and screen engineered bacteria candidates.
  • Analyse data, making detailed observations and interpretation of results.
  • Keep excellent experimental/data records for cross functional teamwork and project learnings.
  • Present findings at internal project team and function meetings.
  • As an employee of an early stage, growing company, you will also have the opportunity to build your experience in commercial and operational aspects of Neobe.

03

Essential qualifications and experience

  • PhD, or equivalent experience, in synthetic biology, molecular biology and/or microbiology.
  • Significant experience and in-depth technical knowledge of practical molecular biology, DNA vector design, with a particular focus on DNA assembly methods.
  • Experience with bacteriology procedures including growth culture, PCR, DNA extraction, plasmid preparation, SDS-PAGE and Western Blotting.
  • Handling and culturing genetically modified microorganisms.
  • Ability to independently curate literature, design and optimise experiments such as microbial growth rate monitoring, enzymatic assays, and creative problem solving.
  • Action-orientated and flexible, to meet challenging deadlines.
  • Excellent teamworking and strong commitment to quality and best practice.

04

Additional knowledge and experience

  • Application of flow cytometry analysis.
  • Familiar with DNA analysis software and synthetic biology bioinformatics tools.
  • Experience working in a commercial biotechnology company, particularly within a small start-up entrepreneurial environment.

05

Personal attributes, mindset and ambitions

  • As a small team it is essential that you enjoy building and fostering strong trusting relationships with team members.
  • Self-management of your time with the ability to organise tasks and deadlines effectively is hugely important and we are looking for someone who does this naturally and instinctively.
  • You can understand the challenges of balancing competing priorities based on business goals to deliver to commercial timelines.
  • You have a pragmatic, can-do and collaborative working style.

06

Benefits

  • Industry-competitive salary based upon your experience.
  • Balancing working and personal life is important to us, and we offer flexibility to support individual needs and work together to balance personal commitments with our business goals and deliverables.
  • State of the art Science & Technology facilities with on-site restaurants with a modern commuting workspace.
  • On site gym and sports facilities.
  • Events and social activities on a regular basis.
  • Coffee and refreshments stations free of charge.
  • We are committed to reviewing our benefits package as we grow with creative plans to introduce an innovative employee-led culture and working life that benefits all.
  • Our company culture is, and will always be, inclusive. We will not discriminate based upon gender identity, race, nationality, skin colour, age, disability, relationship status, sexual orientation, or any other legally protected right or status.

Applying

So, what’s next?

We like to keep our recruitment processes seamless and timely. We do ask for you to provide a cover note telling us why Neobe is where you would like to work and why you are the right person for us. Please send this along with your CV with the name of the position on the subject line. Our commitment is that we will review and respond to every application and keep you informed of progress should you be successfully selected to explore this opportunity with us.

info@neobetherapeutics.com

Please note that Neobe does not accept applications from recruitment agencies.