SENIOR SCIENTIST – SYNTHETIC BIOLOGY      

This is a newly created, full time, permanent role based at Neobe’s laboratory within the Stevenage Bioscience Catalyst, in Stevenage, Hertfordshire.

About us:

Following a significant milestone in our ambitious and exciting growth plans, achieving a successful seed round of over $2m, we are ready to grow our team to advance our pioneering work in immuno-oncology.

Neobe Therapeutics is an innovation-driven Biopharmaceutical start-up developing the next generation of therapeutics in Oncology. At Neobe we are engineering safe strains of tumour colonising bacteria to locally remove stromal barriers to infiltration in immune excluded tumours. Bacteria have been shown to colonise, proliferate and deliver payloads to tumours, making them the ideal candidate for this approach. We are designing them to respond to the local tumour physiological conditions to ensure localised delivery of a stromal remodelling payload.

The Opportunity: Senior Scientist – Synthetic biology

Are you looking for a role where you will have the opportunity to work closely alongside experts in their field, expanding your skill set and supporting your personal development?

Do you have an entrepreneurial spirit with an innovative approach and thrive in a fast paced, dynamic environment?

Are you comfortable and enjoy working primarily in the lab?

Do you have experience working at a senior level with a range of synthetic and molecular biology techniques to engineer, screen and select next generation therapeutics?

Are you ready to be responsible for designing and executing experiments to engineer, select and test our new live engineered bacteria as therapeutic agents in vitro and in vivo?

Please read on for further details on the role and how to apply if this sounds like the perfect next move in your career.

Your key areas of responsibility and accountabilities

❖     Engineering bacteria and performing molecular biology techniques to develop a cloning platform for screening selected biosensors.

❖     Lead planning and execution of in vitro and ex vivo complex experimental work to test and screen engineered bacteria candidates.

❖     Analyse data, making detailed observations and interpretation of results.

❖     Keep excellent experimental/data records for cross functional teamwork and project learnings.

❖     Present findings at internal project team and function meetings.

❖     As an employee of an early stage, growing company, you will also have the opportunity to build your experience in commercial and operational aspects of Neobe.

Essential qualifications and experience that you will be able to demonstrate at interview:

❖     PhD, or equivalent experience, in synthetic biology, molecular biology and/or microbiology.

❖     Significant experience and in-depth technical knowledge of practical molecular biology, DNA vector design, with a particular focus on DNA assembly methods.

❖     Experience with bacteriology procedures including growth culture, PCR, DNA extraction, plasmid preparation, SDS-PAGE and Western Blotting.

❖     Handling and culturing genetically modified microorganisms.

❖     Ability to independently curate literature, design and optimise experiments such as microbial growth rate monitoring, enzymatic assays, and creative problem solving.

❖     Action-orientated and flexible, to meet challenging deadlines.

❖     Excellent teamworking and strong commitment to quality and best practice.

Additional knowledge and experience to support and prioritise your application:

❖     Application of Flow cytometry analysis.

❖     Familiar with DNA analysis software and synthetic biology bioinformatics tools.

❖     Experience working in a commercial biotechnology company, particularly within a small start-up entrepreneurial environment.

Your Personal attributes, mindset and ambitions:

❖    As a small team it is essential that you enjoy building and fostering strong trusting relationships with team members. 

❖     Self-management of your time with the ability to organise tasks and deadlines effectively is hugely important and we are looking for someone who does this naturally and instinctively.

❖     You can understand the challenges of balancing competing priorities based on business goals to deliver to commercial timelines.

❖     You have a pragmatic, can-do and collaborative working style.

Benefits

❖     Industry-competitive salary based upon your experience.

❖     Balancing working and personal life is important to us, and we offer flexibility to support individual needs and work together to balance personal commitments with our business goals and deliverables.

❖     State of the art Science & Technology facilities with on-site restaurants with a modern commuting workspace.

❖     On site gym and sports facilities.

❖     Events and social activities on a regular basis.

❖     Coffee and refreshments stations free of charge.

❖     We are committed to reviewing our benefits package as we grow with creative plans to introduce an innovative employee-led culture and working life that benefits all.

❖     Our company culture is, and will always be, inclusive.  We will not discriminate based upon gender identity, race, nationality, skin colour, age, disability, relationship status, sexual orientation, or any other legally protected right or status.

So, what's next?

Are you already imagining yourself joining our team?

Good, because we can't wait to hear from you.

We like to keep our recruitment processes seamless and timely. We do ask for you to provide a cover note telling us why Neobe is where you would like to work and why you are the right person for us. Please send this along with your CV to info@neobetherapeutics.com with the name of the position on the subject line.

Our commitment is that we will review and respond to every application and keep you informed of progress should you be successfully selected to explore this opportunity with us.

This application period is open from Monday, 15th April 2024 to Friday, 26th April2024, and we will be reviewing applications continuously.